An article I wrote is in “Article in press” publishing on December 1st. Title “Migraine Cause and Treatment” in the Journal of Mental Health in Family Medicine.
Migraine Cause and Treatment
Background: Research shows that migraine brains have hyperactive sensory organs and multiple sensory receptor connections. Hyper activity of these organs needs extra supply of nutrition to support increased electrical activity. Today’s medicines reduce or prevent the functioning of these neurons by blocking essential voltage dependent calcium or sodium channel instead of providing nutrients. We asked: if we provide support for extra electrical activity of migraineurs, would it prevent migraines without the use of medicines?
Methods: We reviewed published literature and conducted research over 6 months studying 650 volunteer migraineurs in a migraine-research Facebook group. Participants were screened for migraine types, answered a questionnaire on medical conditions, medicines used, and lifestyle. They were provided instructions on the use of the migraine protocol and were evaluated weekly.
Findings: Migraine frequency appears to be exacerbated by carbohydrate-rich and salt- and water-poor diets and may be worsened by medicines that block voltage gated calcium or sodium channels. Stopping these medicines, reducing carbohydrates and increasing saline in electrolytes appears to prevent and/or stop migraines.
Conclusions: H2O and Na+ efflux from cells caused by glucose, electrolyte mineral (Na+, Cl–, K+) ratio may be disrupted in carbohydrate heavy diets causing migraines. Changes to diet that include increased salt intake along with reduced carbohydrate intake appears to prevent glucose induced electrolyte changes which then decreases migraine frequency. In the present study, all participants who made these dietary changes were able to eliminate migraine medications and remained migraine free.
Enjoy reading the full article! I hope to elicit more than usual turmoil since this article goes against all conventional migraine treatments but it actually works and there are no medicines involved. 🙂
Comments are welcome as always!
About Angela A Stanton, Ph.D.
Angela A Stanton, PhD, is a Neuroeconomist focusing on chronic pain--migraine in particular--physiology, electrolyte homeostasis, nutrition, and genetics. She lives in Southern California. Her current research is focused on migraine cause, prevention, and treatment without the use of medicine. As a forever migraineur from childhood, her discovery was helped by experimenting on herself. She found the cause of migraine to be at the ionic level, associated with disruption of the electrolyte homeostasis, resulting from genetic variations of all voltage dependent channels, gates, and pumps (chanelopathy) that modulate electrolyte mineral density and voltage in the brain. In addition, insulin and glucose transporters, and several other variants, such as MTHFR variants of B vitamin methylation process and many others are different in the case of a migraineur from the general population.
Migraineurs are glucose sensitive (carbohydrate intolerant) and should avoid eating carbs as much as possible. She is working on her hypothesis that migraine is a metabolic disease.
As a result of the success of the first edition of her book and her helping over 5000 migraineurs successfully prevent their migraines world wide, all ages and both genders, and all types of migraines, she published the 2nd (extended) edition of her migraine book "Fighting The Migraine Epidemic: Complete Guide: How To Treat & Prevent Migraines Without Medications". The 2nd edition is the “holy grail” of migraine cause, development, and prevention, incorporating all there is to know. It includes a long section for medical and research professionals. The book is full of academic citations (over 800) to authenticate the statements she makes to make it easy to follow up by those interested and to spark further research interest. It is a "Complete Guide", published on September 29, 2017.
Dr. Stanton received her BSc at UCLA in Mathematics, MBA at UCR, MS in Management Science and Engineering at Stanford University, PhD in Economics with dissertation in neuroscience (culminating in Neuroeconomics) at Claremont Graduate University, fMRI certification at Harvard University Medical School at the Martinos Center for Neuroimaging for experimenting with neurotransmitters on human volunteers, certification in LCHF/ketogenic diet from NN (Nutrition Network), certification in physiology (UPEN via Coursea), Nutrition (Harvard Shool of Public Health) and functional medicine studies. Dr. Stanton is an avid sports fan, currently power weight lifting and kickboxing. For relaxation (yeah.. about a half minute each day), she paints and photographs and loves to spend time with her family of husband of 45 years, 2 sons and their wives, and 2 granddaughters.
Follow her on Twitter at: @MigraineBook, LinkedIn at https://www.linkedin.com/in/angelaastantonphd/ and facebook at https://www.facebook.com/DrAngelaAStanton/
When referring to reducing carbohydrates, do you mean simple carbs, such as refined sugars? Or complex carbs?
Both Suzie. Simple carbs are not permitted at all in a reduced carbs diet, only complex carbs and even within complex, the types of complex carbs are restricted. Grains of any kind are not permitted. Starchy fruits and vegetables are also not permitted. In fact many fruits are not permitted at all. Usually only raspberries and blackberries are allowed and even in tangerines that are small, only half of a small permitted. Only 5 grapes, for example… a really reduced carbs diet is extremely restrictive but it is measured to each individual based on their weight, age. caloric intake needs for health, etc. The current most popular reduced carbs diet is MAD (Modified Atkins Diet) where everything is in ratios of 1 relative to caloric count knowing that 1 gram carbs or protein produce 4 calories and 1 gram fat produces 9. It is a near 2:1 in which the sum of carbs and protein calories approximately equals the fat calories. This is how they start out to reach what is called the 2:1. It is rather complex. But to give you an example, I had mine calculated by a dietitian. My permitted amounts are: 137 gram fat (any fat), 55 grams protein and 12.6 grams carbs (net carbs that is total carbs – fiber = net carbs.
Getting on a diet like this, with daily max 12.6 grams of carbs we are talking a half an apple and it is up… so now you see what “reduced carbs diet” really means… it is not “just” below 50 grams! It is at starvation level to initiate fat burning or the ketogenic process. In the body it is either or. The two cannot work at the same time.
I hope this helps. Thanks for asking a great question!